Overview of collected data

In the BMB Project, in addition to brain image data, various kinds of information about subjects are acquired in order to perform analysis that adds characteristics of subjects.
MRI brin imaging data
The HARP (Harmonized Protocol) is used as the imaging method for MRI. HARP is a harmonized imaging method that minimizes image changes dependent on MRI differences. HARP uses a minimum of 3 sets of brain structure images (T1-weighted images and T2-weighted images) for about 12 minutes, functional MRI images for 10 minutes, and static magnetic field images by spin echo. For higher precision, this includes 20 minutes of functional MRI images, 3 minutes of 3D Arterial Spin Labeling Imaging (Prisma, Skyra, Verio only), 5 minutes of quantitative magnetic field inhomogeneity images (Prisma, Skyra only), and 4 minutes of 2 types of task performance fMRI images (EMOTION, CARIT). Travelling subjects were also imaged using the SRPB (Strategic Research Program for Brain Sciences) protocol to harmonize with past data from the SRPB and using the HCP-CRHD protocol to harmonize with the US HCP.

● Subject attributes, clinical indicators, and subjective evaluation
At the institution where the data will be collected, the basic characteristics and attributes of the subjects (gender, age, dominant hand, educational/employment status, etc.), clinical indicators (diagnosis name, severity, cognitive function, etc.), and subjective evaluations (QoL, well-being, etc.) will be acquired. Standard acquisition indicators are defined within each group of the BMB Project and are somewhat uniform across groups. These are useful for cross-group analyses.
Participating institution
Currently, 13 research groups in Japan are acquiring clinical data and Traveling Subject data according to the measurement and sharing standards decided by this project.

・Institutes in the blue boxes: Measurement and analysis sites for neuropsychiatric disorders
・Institute in the orange boxes: Show analysis support sites
・Institutes listed in boxes with a colored background: Participation in the traveling subject measurement


Site Role               
(System version)
Protocol    Main target population
The University of Tokyo ECS (UTK) Data  acquisition, Analysis Prisma (VE11C) CRHD Adolescent cohort, HP, ASD, Sch, MDD, Epilepsy
The University of Tokyo IRCN (UTI) Data  acquisition, Sharing Prisma (VE11C) CRHD HP, ASD, Sch, MDD, BPD
Advanced Telecommunications Research Institute International (ATR) Data  acquisition, Sharing,  Analysis Prisma (VE11C) CRHD HP
Fukushima Medical University (FUM) Data  acquisition Skyra (VE11C) HARP HP, AD, PD
Tamagawa Academy & University (TMG) HARP setup, Data  acquisition Trio (VB19A) HARP Adolescent cohort
Showa University (SWA) HARP setup ,Data  acquisition Skyra (VE11E) HARP HP, ASD
National Center of Neurology and Psychiatry (NCNP) HARP setup ,Data  acquisition,  Sharing,  Analysis Skyra (VE11E)  HARP HP, Sch, MDD, AD, PD
Juntendo Hospital (JTD) Data  acquisition Prisma (VE11C) HARP HP, PD, MSA, PSP
Osaka University (UOS) Data  acquisition Prisma (VE11C) HARP HP, Chronic pain
Hiroshima University (UHI) HARP setup, Data  acquisition Skyra (VE11C) HARP HP, MDD, BPD
Nagoya University (UNG) Data  acquisition Verio (VB17A) HARP HP, Sch
Kyoto University (UKY) HARP setup, Data  acquisition Skyra (VE11C) HARP HP, AD, PD
Kyoto University Kokoro Research Center (KRC) Data  acquisition Verio (VB17A) HARP HP, Sch, MDD, BPD
RIKEN Center for Biosystems Dynamics Research (BDR) HARP setup, Data Analysis Prisma (VE11C) HARP NA

※The data for UNG (Nagoya University) was obtained by the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project.